Optogeneics-based visual neuroprosthetics
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"…Instead of trying to replace the lost photoreceptor cells—an approach that is usually quite invasive and that has shown limited benefit for advanced stage disease—Nirenberg has developed a method for bypassing the damaged photoreceptor cells entirely and interacting directly with the ganglion cells. She crystallized the complex relationship between visual stimuli and corresponding ganglion cell activity and deciphered the specific neural “codes” that are generated in response to dynamic spatial and temporal visual patterns. Nirenberg invented a computerized eyeglass prosthetic that transmits the codes to the ganglion cells, which then send the codes to the brain. Although still in the early phases of clinical testing, this new, less invasive strategy has obtained very promising results in mice. – See more at: http://www.macfound.org/fellows/899/#sthash.pLhpKnCb.dpuf…"
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